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Node.js is an open-source, cross-platform JavaScript runtime environment, making it ideal for developing I/O intensive web applications such as video streaming sites, single-page applications, and other web-based solutions.

Node.js applications are crafted using JavaScript and can be executed within the Node.js runtime on various platforms, including OS X, Microsoft Windows, and Linux. Node.js offers a library of JavaScript modules that simplifies the development process for web applications.

On the other hand, Angular is a JavaScript framework that uses TypeScript, a compiled, typed, and feature-rich extension of JavaScript. Angular’s primary purpose is to facilitate the creation of user interfaces for both web and mobile applications.

Angular serves as a comprehensive application-design framework and development platform, empowering developers to build efficient and sophisticated single-page applications with ease.