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Django and Flask are both Python web frameworks utilized for developing web applications. Django is classified as a full-stack framework, whereas Flask is considered a microframework. In essence, Django offers a broader range of features prebuilt, whereas Flask is leaner and allows for more customization.
Django is widely adopted for large and intricate web applications, recognized for its robust security features, potent ORM, and well-documented code. On the other hand, Flask finds popularity for smaller and more straightforward web applications, appreciated for its simplicity and adaptability.